Cape Girardeau which is located in the southeastern part of Missouri, USA is the largest city in the County of Cape Girardeau. The city has the most dramatic Mississippi River Tales Mural with 18,000 square feet shopping district. Cape Girardeau car rental is needed in discovering the place. Have a hassle free holiday once you get the service car rental at Cape Girardeau with the most affordable car rental price in town. Enjoy the historical sites at the downtown area when you rent a car at Cape Girardeau that offers unlimited mileage. Cape Girardeau car rental service gives you the benefit like insurance and collision damage waiver. Hire a car at Cape Girardeau to have fun and entertainment while you are on holiday.